what drugs can meet men use to increase testosterone
Testosterone therapy is intended to treat male hypogonadism (low testosterone or "Low T"), a status in which the torso fails to make enough hormones because of a problem with the testicles, pituitary gland or brain. A number of prescription testosterone products are available to care for hypogonadism. Testosterone products come in dissimilar forms, including gels, injectable solutions, patches, pills and pellets implanted under the skin.
Once a patient starts testosterone therapy, the patient usually undergoes lifelong handling. Doctors will monitor the patient's hormone levels every half-dozen months to a twelvemonth. Depending on the patient, the checkups may exist more frequent.
Fast Facts: Use of Testosterone Therapy Over the Years
- American men spend $2 billion on testosterone each year
- Four times as many men used testosterone products in 2014 than in 2000
- In 2013, 2.3 1000000 Americans were being treated with testosterone therapy
- In 2011, nearly one in 25 men in their 60s was taking testosterone
- Prescription sales of testosterone increased from $18 million in 1988 to $1.6 billion in 2011
Types of Testosterone Products
Testosterone tin can be administered in skin patch, skin gel, pill or cream form — or as an injection, a solution applied to the armpit or a patch or a buccal system applied to the upper gum or inner cheek.
While many testosterone products are available just with a prescription, some drug stores and health food stores sell them over the counter. A few of these products too claim to exist all-natural.
Gels (Androgel and Testim)
Testosterone gel is a prescription medication applied straight to a man'south pare —on the shoulders and upper arms and/or abdomen, depending on the brand. Testosterone gel can inadvertently transfer from your trunk to others and tin lead to serious health reactions. To avert such contact, apply testosterone gel to make clean, dry, intact skin that volition be covered by clothing. Wash your hands correct abroad with soap and h2o after applying. In one case the gel has dried, cover the surface area with clothing and keep it covered until you have washed the area well or have showered.
Injections (Depo-Testosterone)
First canonical in 1979, Depo-testosterone is one of the older drugs of its kind on the market. It's a liquid and is designed for injection deep into the gluteal muscle. The active ingredient, testosterone cypionate, is a white or creamy white powder mixed with other ingredients to make a solution. The drug is bachelor in two strengths, 100 mg and 200 mg.
Patches (Androderm)
Testosterone transdermal patches, including Androderm, come as patches to apply to the skin. Patches work best when practical around the aforementioned time each night and are left in identify for 24 hours. Testosterone patches are meant to be worn at all times until replaced with new patches. Androderm patches should exist changed every 24 hours. The old patch should be removed before applying the new i. You should apply the patches to different spots each night and expect at least seven days before re-using a spot.
Capsules (Methyltestosterone and Android)
The testosterone capsules Methyltestosterone and Android have been discontinued simply have been used in men and boys to treat weather caused by lack of hormone, such as delayed puberty, and in women to treat breast cancer that has spread to other parts of the body. Methyltestosterone is a human being-fabricated grade of testosterone. It tin can affect bone growth in boys who are treated for delayed puberty.
Boosters (Testofen)
Manufacturers of testosterone boosters like Testofen accept touted their products as means to increase muscle mass, strength and sex drive in men. Among the near popular testosterone boosters are products that contain some combination of tribulus terrestris, DHEA, zinc and d-aspartic acrid. These ingredients accept been associated with a number of side effects, including aggressiveness, breast enlargement, cholesterol changes, prostate problems and an increased gamble of cardiovascular affliction.
Makers of testosterone products utilise two types of hormones:
- Bioidentical Hormones
- AndroGel and a number of other products contain bioidentical hormones. Scientists create bioidentical hormones in a lab to chemically match the hormone naturally made by the body. In theory, this results in fewer side effects.
- Synthetic Hormones
- Constructed hormones are altered from the original chemic makeup, so they practise not match those made by the body. These types of drugs typically take more side effects.
Why Men Use Testosterone Therapy
Unusually high or low levels of testosterone can significantly affect a man's physical and mental health. Men typically apply testosterone drugs to accost a medical upshot — like Low T or erectile dysfunction— or to enhance their physical performance
Treating Depression T
Testosterone levels in men start to spike during puberty and drop on average by 1 per centum every year after age xxx. Lack of this fundamental sexual practice hormone in older men tin cause health problems, including osteoporosis, loss of muscle mass and strength (sarcopenia), and psychological symptoms. Doctors prescribe testosterone drugs to treat these symptoms.
While declining testosterone levels tend to exist role of normal aging in men, others experience the dip because of disorders of the testicles, pituitary gland and brain that cause hypogonadism. Other factors — such as injury to the testicles, cancer treatments, chronic diseases and stress — can too contribute to low testosterone production.
The FDA approved testosterone as replacement therapy only for men who have low testosterone levels due to disorders that cause hypogonadism. Still, the agency has said testosterone is being widely used to try to save symptoms in men who have low testosterone for no credible reason other than aging — a use for which the benefits and rubber take non been established.
Declining Testosterone Levels past Historic period
Doctors analyze testosterone levels in two categories: total testosterone and costless testosterone. Most testosterone is attached to a protein chosen sex hormone-binding globulin (SHGB). A small amount of testosterone is gratis, and a minor amount regularly attaches and detaches itself from a protein called albumin. Whatever testosterone that is not attached to SHGB is considered free testosterone.
Remedying Erectile Dysfunction
Some men turn to testosterone to increase sex drive and care for erectile dysfunction (ED), which is the inability to get and keep erections. In fact, according to an article published by Harvard Wellness Publications, some doctors used it to treat ED earlier Pfizer released Viagra in 1998.
"It'southward well established that testosterone by itself, for men with sexual dysfunction that includes erectile dysfunction, can better erections in the majority of men who take information technology."
However, just about 5 percentage of men experience ED solely from low testosterone. Low testosterone levels can be a contributing factor to ED just are more likely to reduce sexual desire than cause ED. Many doctors won't consider prescribing testosterone to a patient unless he presents certain other symptoms, too.
Dr. Abraham Morgentaler is an advocate of using testosterone for treating men with sexual dysfunction, including ED.
Morgentaler does admit that some men may require testosterone and Viagra, however, in gild to have adequate erections.
Enhancing Concrete Performance
Because testosterone allows men to increase musculus mass and performance, athletes and body builders use testosterone-boosting supplements and drugs to increase strength and ameliorate recovery time. The practice of using these drugs is called "doping." Athletes employ both synthetic and bioidentical supplements. Body builders in item are known for their use of synthetic hormones to apace increase muscle mass.
"Testosterone can help increase muscle mass in a much faster style. Athletes who employ anabolic steroids may find that they're able to increase their endurance and their strength by doing the aforementioned amount of training equally they would otherwise," Dr. Anthony Yin, an endocrinologist at California Pacific Medical Center in San Francisco, told SF Gate.
However, using performance-enhancing drugs, testosterone included, is illegal in most sports. While the drug is helpful to men who are clinically diagnosed with Low T, men who corruption these drugs solely to heave operation face a number of possible side effects.
Critics and Risks
Every bit utilise of testosterone therapy has increased and then has the amount of business surrounding these products.
Some doctors say that in reality, few men are really diagnosed with clinical hypogonadism, and that many "symptoms" are but a normal part of crumbling. A report published in the Journal of Clinical Endocrinology & Metabolism shows tape numbers of men in the U.S. are turning to testosterone therapy but to increment their sex drive and energy levels.
Critics say that Low T is a condition marketed past drug companies to increase profits. Doctors are concerned that the long-term furnishings have non yet been properly studied and experience there should exist more agreement near what constitutes a normal testosterone level. Because testosterone therapies are not proven treatments, they caution that risks may outweigh benefits for healthy men.
Dr. Lisa Schwartz, a professor at the Dartmouth Institute for Wellness Policy and Clinical Exercise, wrote a paper on drug companies marketing these hormone therapies.
"Nosotros're giving people hormones that we don't know they demand for a disease that we don't know they have, and we don't know if it'll help them or harm them."
Over the years, men have sued the makers of testosterone products after using the therapies and suffering from heart attacks, strokes and blood clots. Meanwhile, researchers have conducted studies to meliorate understand the effects of testosterone therapy.
Recent Clinical Trials
Researchers for a year studied the effect of testosterone treatment on cognition, bone health, anemia and cardiovascular health in 788 men aged 65 or older who had depression testosterone levels that couldn't be explained past anything other than age.
According to the findings, reported in February 2017 in JAMA and JAMA Internal Medicine, testosterone treatment did not have an effect on memory or cognitive abilities, though it appeared to increase hemoglobin levels in men with anemia and improve os density. In addition, a clinical trial establish one year of testosterone treatment in men anile 65 or older with Depression T was associated with a significant increase in coronary avenue plaque, a risk cistron for heart illness.
Heart Attacks and Other Side Effects
Studies take linked testosterone products to serious side effects, prompting the FDA to have action in recent years to warn the public of the potential dangers of these products.
Testosterone therapy is associated with an increased risk for these wellness problems:
- Heart Attacks (mainly in male patients over 65 and patients with diagnosed center disease)
- Stroke
- Blood Clots
- Polycythemia (high levels of red blood cells that can lead to blood clots and stroke)
- Worsening of Sleep Apnea
- Hormonal Imbalance
- Prostate Cancer
Dangers to Women, Children & Pets
Testosterone therapy for men can be dangerous to women and children if they come in contact with the drug by touching the patient's peel. This usually occurs when men use testosterone gel and the awarding site is exposed. Anyone who comes in contact with the application site is at risk of developing side effects.
Women can experience acne or hair growth, and if they are pregnant, the unborn baby may exist harmed.
In 2009, the FDA issued a warning nigh agin effects in children exposed to testosterone gels through contact with application sites. Symptoms included abnormally large genitalia (penis and clitoris), advanced bone age, early puberty and aggressive behavior. Immature boys may fifty-fifty develop enlarged breasts. A doctor should be contacted right away if these symptoms occur.
Pets exposed to testosterone can become fierce and ambitious and develop enlarged genitals.
Source: https://www.drugwatch.com/testosterone/
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